brain health

Research Connects Oral Health to Brain Health

A study published in Neurology establishes a concerning association between poor oral health and various brain-related conditions like stroke, dementia, and cognitive decline.

The study, conducted in Ohasama, Japan, surveyed 172 participants aged 55 and older without memory concerns. It investigated the impact of oral health on brain structures, particularly the hippocampus—a crucial region for memory, learning, and emotion, vulnerable to conditions such as Alzheimer’s disease.

The study commenced with dental examinations to identify periodontitis and assess participants’ teeth count. Initial MRI scans measured hippocampal volume. After four years, follow-up scans tracked cognitive decline levels.


The findings emphasized a significant correlation between oral health indicators and hippocampal changes. Mild periodontitis, coupled with fewer teeth, resulted in accelerated brain atrophy. Conversely, severe periodontitis demonstrated a swifter atrophy rate in individuals with more teeth.

Lead researcher Satoshi Yamaguchi from Tohoku University’s division of aging and geriatric dentistry highlighted the study’s implications. “Retaining more healthy teeth, free from periodontal disease, could safeguard brain health,” Yamaguchi stated. However, he cautioned against retaining numerous teeth affected by severe periodontitis, suggesting potential harm to brain health. Yamaguchi speculated on the possible invasion of brain tissues by periodontal disease pathogens and underscored the role of reduced chewing stimulation in contributing to brain atrophy.

The researchers stressed the importance of regular dental check-ups to manage periodontal disease progression. They recommended considering extractions and suitable denture replacements for severely affected teeth. Yamaguchi’s team hopes these findings encourage better oral care practices to protect brain health in aging populations.


The research opens avenues for future investigations into the mechanisms underlying this association. Exploring the potential pathways through which oral health impacts brain structures could unveil novel strategies for preventing or managing cognitive decline in aging populations.

In essence, this study underscores the profound interconnection between oral health and brain health, emphasizing the significance of comprehensive healthcare strategies that integrate dental care to safeguard cognitive function as individuals age.

Source: Dentistry

1 Comment

    11 January 2024

    This is seriously perfect for you

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