root canal filling materials

Root canal treatment is a common dental procedure aimed at saving a severely infected or damaged tooth. It involves removing the infected pulp from the tooth’s interior, cleaning and shaping the root canals, and then filling them to prevent further infection. The choice of root canal filling material plays a crucial role in the success and longevity of the treatment. In this article, we will delve into the various root canal filling materials, their properties, advantages, disadvantages, and advancements in the field.



Gutta-percha has been the gold standard root canal filling material for decades. It is a natural polymer derived from the sap of the Palaquium gutta tree. Gutta-percha cones are thermoplastic and can be softened with heat for placement into the root canal. Once cooled, gutta-percha solidifies, providing a stable and biocompatible filling.

Advantages of Gutta-Percha

  • Biocompatible: Gutta-percha is well-tolerated by the body, minimizing the risk of adverse reactions.
  • Dimensionally stable: It maintains its shape and seals the root canal effectively.
  • Radiopaque: Facilitates post-treatment assessment through radiographs.


Disadvantages of Gutta-Percha

  • Lack of antimicrobial properties: Gutta-percha does not possess inherent antimicrobial activity.
  • Limited adhesive properties: Requires a sealer to ensure a fluid-tight seal.
  • Susceptible to fracture: In cases of excessive root canal curvature, gutta-percha cones may fracture during placement.


Resin-Based Sealers

Resin-based sealers have gained popularity in recent years due to their improved sealing ability and antimicrobial properties. These sealers are composed of resin monomers, fillers, and additives designed to enhance their physical and chemical properties.

Advantages of Resin-Based Sealers

  • Adhesive properties: Resin-based sealers bond well to both dentin and gutta-percha, providing a superior seal.
  • Antimicrobial activity: Some resin-based sealers contain antimicrobial agents such as chlorhexidine or nanoparticles, reducing the risk of reinfection.
  • Dimensional stability: Resin-based sealers exhibit minimal shrinkage upon setting, maintaining the integrity of the root canal filling.


Disadvantages of Resin-Based Sealers

  • Technique sensitivity: Proper application and mixing of resin-based sealers are essential to ensure optimal results.
  • Potential cytotoxicity: Some resin-based sealers may exhibit cytotoxic effects on periapical tissues if not properly polymerized.


Bioceramic Sealers

Bioceramic sealers represent a significant advancement in root canal filling materials. These sealers are composed of biocompatible calcium silicates, calcium phosphates, and zirconium oxide, which react with moisture to form a hydroxyapatite-like structure.

Advantages of Bioceramic Sealers

  • Biocompatibility: Bioceramic sealers exhibit excellent biocompatibility with periapical tissues.
  • Bioactivity: They promote the formation of hydroxyapatite, facilitating the sealing of dentinal tubules and enhancing periapical healing.
  • Self-sealing properties: Bioceramic sealers expand slightly upon setting, effectively filling voids and microgaps in the root canal system.


Disadvantages of Bioceramic Sealers

  • Setting time: Bioceramic sealers have a longer setting time compared to resin-based sealers, requiring adequate isolation to prevent contamination.
  • Cost: Bioceramic sealers are typically more expensive than traditional gutta-percha and resin-based sealers.


Mineral Trioxide Aggregate (MTA)

MTA is a versatile root canal filling material with a wide range of applications in endodontics. It is composed of fine hydrophilic particles, including tricalcium silicate, dicalcium silicate, tricalcium aluminate, and bismuth oxide.

Advantages of MTA

  • Biocompatibility: MTA is well-tolerated by periapical tissues and promotes favorable healing responses.
  • Sealing ability: MTA forms an excellent seal when properly condensed into the root canal space.
  • Bioactivity: Similar to bioceramic sealers, MTA stimulates the formation of hydroxyapatite, enhancing periapical repair.


Disadvantages of MTA

  • Handling characteristics: MTA has a sandy consistency that can be challenging to manipulate and condense within the root canal.
  • Discoloration: MTA may discolor over time, particularly in teeth with open apices, affecting the aesthetic outcome.


Zinc Oxide-Eugenol (ZOE)

Zinc oxide-eugenol-based sealers have been used in endodontics for many years. These sealers contain zinc oxide powder and eugenol, a natural oil extracted from cloves, which acts as a plasticizer.

Advantages of ZOE

  • Sedative properties: Eugenol exhibits mild analgesic and antibacterial properties, providing a soothing effect on inflamed periapical tissues.
  • Easy manipulation: ZOE sealers have a creamy consistency that is easy to manipulate and place within the root canal system.
  • Cost-effective: ZOE sealers are more affordable compared to resin-based or bioceramic sealers.


Disadvantages of ZOE

  • Solubility: ZOE sealers are susceptible to dissolution in the presence of moisture, compromising their sealing ability over time.
  • Lack of adhesion: They do not bond well to dentin or gutta-percha, necessitating the use of a core material for reinforcement.


Further Research and Advancements in Root Canal Filling Materials

Further research and advancements in endodontic materials are continually expanding the options available to clinicians, with the aim of enhancing treatment outcomes and patient satisfaction. As technology evolves, newer materials are being developed to address the limitations of traditional options and improve the long-term success of root canal therapy.

One area of ongoing research focuses on the development of bioactive materials that not only seal the root canal space but also actively promote tissue regeneration and healing. Bioactive materials stimulate the formation of hydroxyapatite, the main mineral component of natural tooth structure, which can enhance the integration of the root canal filling with surrounding tissues and facilitate periapical healing. These materials hold great promise for improving the long-term prognosis of endodontically treated teeth, particularly in cases of apical periodontitis or periapical lesions.

Another emerging trend in endodontic materials is the use of nanoparticles for enhanced antimicrobial properties. Nanoparticles have been incorporated into various root canal filling materials, including resin-based sealers and bioceramics, to improve their ability to eliminate bacteria within the root canal system. Silver nanoparticles, in particular, have shown promise due to their broad-spectrum antimicrobial activity against a wide range of bacteria commonly associated with endodontic infections. By incorporating nanoparticles into root canal filling materials, clinicians can potentially improve the eradication of bacteria within the root canal system and reduce the risk of treatment failure due to persistent infection.

In addition to advancements in materials, innovations in delivery systems and techniques are also contributing to the evolution of endodontic therapy. For example, the development of warm vertical compaction techniques has improved the adaptation of gutta-percha within the root canal space, resulting in a more effective seal and reduced risk of postoperative complications. Similarly, the use of ultrasonic and sonic activation devices has enhanced the flow and adaptation of root canal sealers, improving the quality of the root canal fillings and reducing the likelihood of voids or gaps that could compromise treatment outcomes.

As research continues to advance, future developments in endodontic materials are likely to focus on further improving biocompatibility, sealing ability, and antimicrobial properties while addressing practical considerations such as handling characteristics and cost-effectiveness. By staying abreast of these developments and incorporating innovative materials and techniques into clinical practice, endodontists can continue to provide high-quality care and optimize outcomes for their patients undergoing root canal therapy.



Root canal filling materials play a pivotal role in the success of endodontic therapy. While gutta-percha remains a widely used material, recent advancements have introduced a variety of options with improved sealing ability, antimicrobial properties, and biocompatibility. Resin-based sealers, bioceramic sealers, MTA, and zinc oxide-eugenol sealers each offer unique advantages and disadvantages, allowing clinicians to tailor their choice based on the specific clinical scenario and patient needs. Continued research and development in root canal filling materials promise further advancements, ultimately improving the outcomes of endodontic treatment.

1 Comment

  • Ghiasudin Anwari
    11 July 2024

    I studied the number of canals per tooth, root canal treatment, rotary in root canals, paint after root canals, and rubber dam application and all steps of the treatment process it was very useful for the clinical action and operation.

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