angular cheilitis

Angular cheilitis, also known as perleche or angular stomatitis, is a common condition characterized by inflammation, redness, fissures, and cracking at the corners of the mouth. This discomforting condition can be bothersome, impacting one’s ability to eat, speak, and smile comfortably. Understanding its causes, symptoms, available treatments, and preventive measures is crucial for managing and alleviating its effects.


Causes of Angular Cheilitis

The exact cause of angular cheilitis can be multifactorial, often involving a combination of various factors:

  • Fungal or Bacterial Infections
  • Moisture and Saliva
  • Nutritional Deficiencies
  • Denture Use
  • Skin Conditions


Fungal or Bacterial Infections

Candida albicans (yeast) and bacterial species like Staphylococcus aureus are commonly associated with angular cheilitis.

Moisture and Saliva

Excessive saliva accumulation at the corners of the mouth due to drooling, lip-licking, or ill-fitting dentures creates a favorable environment for fungal or bacterial growth.

Nutritional Deficiencies

Deficiencies in vitamins like B vitamins (especially B2, B3, B6, and B12), iron, and zinc can weaken the immune system and contribute to angular cheilitis.

Denture Use

Poorly fitting dentures can cause skin irritation and trapping of moisture, leading to angular stomatitis.

Skin Conditions

Eczema, psoriasis, or other skin conditions can predispose individuals to angular cheilitis due to compromised skin integrity.



The most prominent symptoms of angular cheilitis include:

  • Pain, tenderness, or soreness at the corners of the mouth
  • Redness, inflammation, or swelling
  • Cracks, fissures, or splits in the skin, sometimes accompanied by bleeding
  • Dryness or itching
  • Formation of crusts or sores


Treatments for Angular Cheilitis

Treatment for angular cheilitis largely depends on the underlying cause. Here are various approaches that can be effective:

  • Antifungal or Antibacterial Creams
  • Topical Corticosteroids
  • Vitamin and Mineral Supplements
  • Moisturizers and Barrier Creams
  • Denture Adjustment


Antifungal or Antibacterial Creams

Topical antifungal or antibacterial creams or ointments, such as clotrimazole or miconazole, can help clear up fungal or bacterial infections.

Topical Corticosteroids

These can be prescribed to reduce inflammation and promote healing, especially in cases associated with skin conditions like eczema.

Vitamin and Mineral Supplements

Supplementing with B vitamins, iron, and zinc can help if deficiencies are contributing to the condition.

Moisturizers and Barrier Creams

Applying petroleum jelly, beeswax, or other emollients can help protect the skin and prevent moisture accumulation.

Denture Adjustment

Ensuring well-fitted dentures or seeking dental assistance for adjustments can prevent irritation and moisture accumulation.


Preventive Measures

Taking preventive measures can significantly reduce the risk of developing angular cheilitis:

  • Hygiene
  • Nutrition
  • Dental Care
  • Stay Hydrated
  • Avoid Irritants



Keep the corners of the mouth clean and dry. Avoid excessive licking of lips.


Maintain a balanced diet rich in vitamins and minerals to support immune health.

Dental Care

Ensure proper oral hygiene and regular dental check-ups, especially if wearing dentures.

Stay Hydrated

Drink an adequate amount of water to prevent dehydration.

Avoid Irritants

Limit exposure to potential irritants like harsh lip products or toothpaste that may exacerbate the condition.


When to Seek Medical Advice

While mild cases of angular cheilitis can often be managed with home remedies, it’s essential to consult a healthcare professional if:

  • The condition persists for more than a few days despite home treatment.
  • There’s severe pain, swelling, or bleeding.
  • The sores become infected or spread.


Risk Factors and Complications

Several factors can increase the likelihood of developing angular cheilitis:

  • Age
  • Denture Wearers
  • Weakened Immune System
  • Nutritional Deficiencies
  • Climate and Weather



Elderly individuals, due to changes in skin integrity and immune function, are more susceptible.

Denture Wearers

Ill-fitting dentures or poor oral hygiene can contribute to the condition.

Weakened Immune System

Conditions like HIV/AIDS, diabetes, or autoimmune disorders can increase vulnerability to infections, including angular cheilitis.

Nutritional Deficiencies

Poor diet or malabsorption disorders can lead to deficiencies, exacerbating the risk.

Climate and Weather

Cold, dry weather or excessive moisture can aggravate the condition.

If left untreated or in severe cases, angular cheilitis can lead to complications such as secondary bacterial infections, scarring, or persistent discomfort affecting eating and speaking.


Home Remedies and Care

In addition to medical treatments, certain home remedies and self-care practices can complement the management of angular cheilitis:

  • Honey
  • Aloe Vera
  • Good Oral Hygiene
  • Warm Compresses



Applying raw honey to the affected area can offer antimicrobial benefits and promote healing.

Aloe Vera

Aloe vera gel has soothing properties and can aid in reducing inflammation.

Good Oral Hygiene

Regularly brush teeth and gently clean around the mouth with a soft toothbrush to prevent bacterial buildup.

Warm Compresses

Applying a warm, damp cloth to the affected area can provide relief from discomfort.



Angular cheilitis, though not usually serious, can cause discomfort and affect daily activities. Understanding its causes, symptoms, treatments, and preventive measures is crucial for effective management. By maintaining good oral hygiene, addressing nutritional deficiencies, and seeking appropriate medical advice when needed, individuals can alleviate the discomfort associated with this condition and prevent its recurrence.

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